Sunday, February 18, 2007

"Bridge Too Far"

Prof Charles Warlow had come to India to give a talk on pit falls in clinical trials. Errors in journals as reputed as NEJM …

He said he doesn’t encounter neurocysticercosis, or CVTs like we see here. HIV cases are rare out there! He continued …

“You have got 1.1 billion people in India. Every patient you treat should be in a randomized trial which should give you answers that are directly applicable to your population rather than importing data generated in the west.”

- Charles Warlow
Professor of Medical Neurology, Western General Infirmary, Crewe Road, Edinburgh

May be we should have a central body that can coordinate very large multi-institutional clinical trials in India – funding, monitoring and analysis. Because trials done by an individual or an institute are such a waste of time [other than an exercise in systematic fabrication of data.]

Ok. Now let’s take a look at this –

Decompressive Surgery After MCA Stroke Reduces Death, Improves Functional Outcome - Pooled analysis of 3 trials of randomized patients.
http://mp.medscape.com/cgi-bin1/DM/y/hBI6k0NQNoE0D2H0ILWY0E2

Hope too many neurologist don’t read this! Because I’m sure not too many neurosurgeons like the idea.

Do they still keep that stroke ward bed ready or is it NPOW?
May be I’ll ask visiting-Prof Venky!

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